Eine unvoreingenommene Sicht auf mephedrone drug user experience
Eine unvoreingenommene Sicht auf mephedrone drug user experience
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Subjects were admitted to the Clinical Research Unit facilities at 0700 hours after an overnight fast. Upon arrival, they were questioned about any Veranstaltung that could affect their participation. They were requested to refrain from using any psychoactive drug, a minimum of 7 days prior to the study and throughout it, and from ingesting caffeinated products and alcohol in the 24 h prior to sessions.
Videos by VICE Meanwhile in the U.S., mephedrone and other synthetic cathinones such as methylone and MDPV—some of which were sold as “bath salts”—and later alpha-PVP, which became known as “flakka,” became popular.
Mephedrone (4-methylmethcathinone) is an empathogen-stimulant drug, which means it speeds up the messages travelling between the brain and body. Mephedrone also increases an individual’s feeling of empathy and kindness and enhances feelings of being socially accepted and connected to others.1
From all appearances, mephedrone is not a passing fad. It’s here to stay, and looks likely to add yet another name to the Tücke of Harte nuss drugs that prohibition struggles so ineffectually to deal with.
This, coupled with overwhelming cravings for more of the drug, can keep a user rein a destructive cycle that is very difficult to break.
Heart and circulatory problems: overstimulation has the capacity to put too much pressure on the heart and surrounding tissues. Poor circulation can turn lips and fingertips blue as well.
One team of researchers used high-precision drilling and some very fine needles to sample the brain chemistry of rats that were high on mephedrone. They found the drug caused a fast and vigorous release of neurotransmitters into parts of the brain strongly involved rein craving and addiction.
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These were the locations of “transporters”, neural structures that pick up and recycle neurotransmitters after they’ve done their thing. Clogging up these transporters can make neurotransmitters hang around for longer than they should, which increases the effect they have on the brain.
Owing largely to its recent emergence, there are very few formal pharmacodynamic or pharmacokinetic studies of mephedrone. A single report by Kehr et al. (2011) indicates that mephedrone causes DA release rein the nucleus accumbens. Beyond this, clinical and anecdotal reports are the primary source of information concerning mephedrone. This lack of information is problematic for public health policy makers and law enforcement organizations as they attempt to develop and implement appropriate strategies to deal with the recreational use and what is mephedrone drug abuse of mephedrone and related drugs. Of further concern, it has been suggested that mephedrone may resemble dangerous drugs such as methcathinone, copyright, or METH.
Users of mephedrone say that it gives a feeling of stimulation, and that it boosts the following functions:
It may increase energy, focus, and alertness. It is important to Zensur that individual experiences may vary, and the effects of this product have not been extensively studied.
Users may take larger doses to get the same effect, so it cannot Beryllium seen as less harmful than ecstasy or amphetamines.